Roxithromycin 66

+

(Roxithromycine) -,,,,,,. CAS: 80214-83-1:. : - (). 50S,,,,. ,. (), 15. 50., Cmax AUC 15. 1,5-2 cmax 150 6,6 / 300 20. 300 (60-79) AUC T1 / 2,,,. 1/2 Cmax, AUC T1 / 2 (25),. ,,. . , 100, 400 135 //,. 180 //. . , .. Bordetella pertussis, Borrelia burgdorferi, Moraxella (Branhamella) catarrhalis, Campylobacter coli, Campylobacter jejuni, Chlamydia trachomatis, Chlamydia psittaci, Chlamydia pneumoniae, Clostridium spp. .. Clostridium perfringens, Corynebacterium diphtheriae, Enterococcus, Gardnerella vaginalis, Staphylococcus aureus, Neisseria meningitidis, Helicobacter pylori, Legionella pneumophila, Listeria monocytogenes, Mycoplasma pneumoniae, Pasteurella multocida, Peptostreptococcus, Porphyromonas, Propionibacterium acnes, Rhodococcus eGUI, Streptococcus spp. .. Streptococcus pneumoniae. Haemophilus influenzae, Ureaplasma urealyticum, Vibrio cholerae. Entérobactéries spp. spp Pseudomonas. Acinetobacter spp. Bacteroides fragilis, Staphylococcus aureus, Fusobacterium, Mycoplasma hominis, Nocardia. : -,: - (,,,,,,,,,,,), (,,,, ..,), (,,,,,) () (,),,,). ,. . : (..), (2), (.). :. : (). (). :,,, / (),,,,,,. :,,,,, /,. :,,,,,,,. :,,,,. :. . AUC 1/2 (). , (). (). , (,,). ,,,, QT /. ,,,. :,. . : 21). . . 150 1. :,,. ,,,. . , / (Roxithromycin) /.